| Player | First | Overall | Last |
| Luís Fabiano (Sevilla) | 10 | | 24 | (2) | 7 | (2) |
| Llorente (Valladolid) | 10 | | 17 | | 3 | |
| Güiza (Mallorca) | 9 | | 27 | | 7 | |
| Nihat (Villarreal) | 8 | | 18 | | 5 | |
| Raúl (Real Madrid) | 7 | (1) | 18 | (3) | 1 | (1) |
| Van Nistelrooy (Real Madrid) | 6 | (1) | 16 | (3) | 3 | |
| Agüero (Atlético Madrid) | 6 | | 20 | | 5 | |
| Forlán (Atlético Madrid) | 6 | | 16 | (2) | 4 | |
| Henry (Barcelona) | 6 | | 12 | | 1 | |
| Milito (Zaragoza) | 5 | (2) | 15 | (5) | 4 | (2) |
| Vílla (Valencia) | 5 | (1) | 18 | (2) | 4 | |
| Negredo (Almería) | 5 | (1) | 12 | (2) | 4 | (1) |
| Ricardo Oliveira (Zaragoza) | 5 | | 17 | | 6 | |
| Sinama-Pongolle (Recreativo Huelva) | 5 | | 10 | | 1 | |
| Iván Alonso (Real Murcia) | 4 | (1) | 10 | (3) | 1 | |
| Felipe Melo (Almería) | 4 | (1) | 7 | (1) | 1 | |
| Arango (Mallorca) | 4 | | 12 | | 2 | |
| Tchite (Racing Santander) | 4 | | 8 | | 4 | |
| Sergio (Deportivo) | 3 | (3) | 5 | (4) | 0 | |
| Rossi (Villarreal) | 3 | (1) | 11 | (5) | 3 | (1) |
| Messi (Barcelona) | 3 | (1) | 10 | (4) | 2 | (2) |
| Adúriz (Athletic Bilbao) | 3 | (1) | 7 | (1) | 2 | |
| González (Real Betis) | 3 | (1) | 6 | (1) | 1 | |
| Pablo (Getafe) | 3 | (1) | 3 | (1) | 0 | |
| Kanouté (Sevilla) | 3 | | 19 | (2) | 5 | (1) |
| Eto'o (Barcelona) | 3 | | 16 | | 4 | |
| Robinho (Real Madrid) | 3 | | 11 | | 3 | |
| Bojan (Barcelona) | 3 | | 10 | | 2 | |
| Xisco (Deportivo) | 3 | | 9 | | 2 | |
| Riga (Levante) | 3 | | 8 | (2) | 0 | |
| Franco (Villarreal) | 3 | | 8 | | 3 | |
Primera División 2007/08