Round 21
|
| Saturday, 13 September 2008 |
| Rubin - Dinamo |
| FK Moskva - Spartak |
| Saturn - Tom |
| Terek - Zenit |
| Sunday, 14 September 2008 |
| CSKA - Luch-Energia |
| Shinnik - Amkar |
| Krylia Sovetov - Khimki |
| Spartak Nalchik - Lokomotiv |
Round 22
|
| Saturday, 20 September 2008 |
| Dinamo - Shinnik |
| Amkar - Krylia Sovetov |
| Khimki - Saturn |
| Luch-Energia - Lokomotiv |
| Sunday, 21 September 2008 |
| Spartak - Rubin |
| Zenit - CSKA |
| FK Moskva - Spartak Nalchik |
| Tom - Terek |
Round 23
|
| Saturday, 27 September 2008 |
| Lokomotiv - Zenit |
| Shinnik - Spartak |
| Krylia Sovetov - Dinamo |
| Spartak Nalchik - Luch-Energia |
| Sunday, 28 September 2008 |
| CSKA - Tom |
| Rubin - FK Moskva |
| Saturn - Amkar |
| Terek - Khimki |
Premier Liga 2008