| Player | First | Overall | Last |
| Dichio (Toronto FC) | 4 | | 5 | | 0 | |
| Barrett (Chicago Fire) | 4 | | 5 | | 0 | |
| Emilio (D.C. United) | 3 | | 10 | | 5 | |
| Cooper (FC Dallas) | 3 | | 8 | | 2 | |
| Ralston (N.E. Revolution) | 3 | | 6 | (1) | 1 | |
| Ching (Houston Dynamo) | 3 | | 6 | | 1 | |
| Cristman (N.E. Revolution) | 3 | | 6 | | 0 | |
| Moreno (D.C. United) | 2 | (2) | 6 | (4) | 0 | |
| Barros Schelotto (Columbus Crew) | 2 | (2) | 3 | (3) | 0 | |
| Donovan (L.A. Galaxy) | 2 | | 11 | (3) | 2 | |
| Moreno (Columbus Crew) | 2 | | 6 | | 2 | |
| Kljestan (Chivas USA) | 2 | | 5 | | 0 | |
| De Rosario (Houston Dynamo) | 2 | | 4 | (1) | 2 | (1) |
| Dube (N.E. Revolution) | 2 | | 4 | | 2 | |
| Van Den Bergh (New York) | 2 | | 4 | | 1 | |
| Findley (Real Salt Lake) | 2 | | 3 | | 1 | |
| Rolfe (Chicago Fire) | 2 | | 3 | | 0 | |
| Espindola (Real Salt Lake) | 2 | | 3 | | 0 | |
| Conrad (K.C. Wizards) | 2 | | 3 | | 0 | |
| Moffat (Columbus Crew) | 2 | | 2 | | 0 | |
| Magee (New York) | 1 | (1) | 1 | (1) | 0 | |
| Buddle (L.A. Galaxy) | 1 | | 10 | | 2 | |
| Beckham (L.A. Galaxy) | 1 | | 5 | | 3 | |
| McManus (Colorado Rapids) | 1 | | 4 | | 3 | |
| Cummings (Colorado Rapids) | 1 | | 4 | | 1 | |
| Marsch (Chivas USA) | 1 | | 4 | | 1 | |
| Gallardo (D.C. United) | 1 | | 4 | | 1 | |
| López (K.C. Wizards) | 1 | | 3 | (1) | 2 | (1) |
| Altidore (New York) | 1 | | 3 | | 2 | |
| Razov (Chivas USA) | 1 | | 3 | | 1 | |
| Flores (Chivas USA) | 1 | | 3 | | 1 | |
Major League 2008